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Effects of Botulinum Toxin A on Cytokine Synthesis in a Cell Culture Model of...

Conclusions The present data do not add evidence to suggest a significant therapeutic role of botulinum toxin A injections for cutaneous wound healing beyond chemoimmobilization. Read more: Effects of...

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Jun N-terminal kinase as a potential molecular target for prevention and...

Conclusions These data identify JNK as a downstream mediator of the pro-fibrotic effects of of TGFβ and PDGF in SSc fibroblasts. Selective inhibition of JNK by CC-930 exerted potent antifibrotic...

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Complications of injectable fillers and neurotoxins

ABSTRACTAll cosmetic injectable products are associated with the risk of both early and delayed complications. Early and expected side effects include swelling, bruising, and erythema at the injection...

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Glycyrrhizic acid (GA), a triterpenoid saponin glycoside alleviates...

Abstract: Glycyrrhizic acid (GA), a triterpenoid saponin glycoside from the roots and rhizomes of licorice is used in traditional and modern medicine for the treatment of numerous medical conditions...

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Dermal Application of Nitric Oxide In Vivo: Kinetics, Biological Responses,...

Authors: Opländer C, Römer A, Paunel-Görgülü A, Fritsch T, van Faassen EE, Mürtz M, Bozkurt A, Grieb G, Fuchs P, Pallua N, Suschek CV Abstract Many local hemodynamic and vascular disorders may be...

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The 12/15-lipoxygenase pathway counteracts fibroblast activation and...

Conclusions These data indicate that 12/15-LO and its metabolites have a prominent antifibrotic role during dermal fibrosis. View post: The 12/15-lipoxygenase pathway counteracts fibroblast activation...

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Topical application of disodium isostearyl 2‐O‐L‐ascorbyl phosphate, an...

CONCLUSIONS AND IMPLICATIONSAscorbic acid, known to inhibit Cav3.2 channels, suppressed neuropathic hyperalgesia. DI‐VCP ointment for topical application may be of benefit in the treatment of...

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Interleukin‐18 system plays an important role in keloid pathogenesis via...

Conclusions  The present study has proven that the IL‐18 system plays an important role in keloid pathogenesis via epithelial–mesenchymal interactions. View original post here: Interleukin‐18...

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Clinical implementation of a novel wound assessment tool (Silhouette Star)...

Purpose: To test the cost effectiveness and efficacy of Dermagraft in the treatment of non-healing DFUs within a clinical setting. To assess the potential advantages of using a more advanced system of...

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A Multicenter, Double‐Blind, Placebo‐Controlled Trial of Autologous...

ConclusionAzficel‐T is safe and effective for the treatment of NLF wrinkles. The availability of autologous cell therapy marks the beginning of a new phase in aesthetic therapy. (Source: Dermatologic...

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